Gretchen Harms, Christopher Hunter Lab. Tiffany Weinkopff, Phillip Scott Lab. Adriana Mategazza, Mickey Marks Lab. Trainees are encouraged to submit an abstract. Recognizing the need to create an environment where researchers could be adequately trained in the multifaceted aspects of immunobiology, Penn became the first medical school to establish a separate degree-granting PhD program in Immunology.
The human olfactory cleft mucus proteome and its age-related changes. Sci Rep. Biomarkers in Chronic Rhinosinusitis with Nasal Polyps. Immunol Allergy Clin North Am. Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes.
J Pathog. The role of bitter and sweet taste receptors in upper airway innate immunity: Recent advances and future directions. Curr Otorhinolaryngol Rep. Upenn Jul J Vis Exp.
Solitary chemosensory cells are a primary epithelial source upenn IL allergy patients with chronic rhinosinusitis with nasal polyps. J Jpenn Clin Immunol. Epub May Preoperative Lund-Mackay computed tomography score is associated with preoperative symptom severity and predicts quality-of-life outcome trajectories after sinus surgery.
Epub Mar 8. Solitary chemosensory cells producing interleukin and group-2 innate lymphoid cells are enriched in chronic rhinosinusitis with nasal polyps. Bitter and sweet taste tests are reflective of disease status in chronic rhinosinusitis. J Allergy Clin Immunol Pract. Am J Pathol. Epub Feb Front Immunol. Front Cell Infect Microbiol.
Medical management of chronic rhinosinusitis - a review of traditional and novel medical therapies. Expert Opin Investig Drugs. Epub Sep 5. Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells.
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Relative susceptibility upenn airway organisms to antimicrobial effects of nitric oxide. Effects of ophthalmologic solutions on sinonasal ciliated epithelium.
Denatonium-induced sinonasal bacterial killing may play a role in chronic rhinosinusitis outcomes. Am Allergy Rhinol Allergy. Appl Immunohistochem Mol Morphol. Myrtol standardized affects mucociliary clearance. Epub Nov Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity. Int J Mol Sci.
Expression of dermcidin in human sinonasal secretions. Cohen NA. The genetics of the bitter taste receptor T2R38 in upper airway innate immunity and implications for chronic rhinosinusitis.
New insights into upper airway innate immunity. Human upper airway epithelium produces nitric oxide in response to Staphylococcus epidermidis. Laryngoscope Investigative Otolaryngology. Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients. Medical management of chronic kpenn - an update. Expert Rev Clin Pharmacol.
Epub Dec Sinus irrigations before and after surgery-Visualization through computational fluid dynamics simulations. A role for airway taste receptor modulation in the treatment of upper respiratory infections. Expert Rev Respir Med. Epub Jan Bitter taste bodyguards.
Sci Am. TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis. Aallergy Allergy Asthma Rep. Chronic rhinosinusitis pathogenesis. Staphylococcus aureus triggers nitric oxide production in human upper airway epithelium. Epub Jun Different clinical factors associated with Staphylococcus aureus and Pseudomonas aeruginosa in chronic rhinosinusitis. Epub Apr Biofilm-forming bacteria and quality of life improvement after sinus surgery. Epub Mar Corticosteroid use does not alter nasal mucus glucose in chronic rhinosinusitis.
Otolaryngol Head Neck Surg. Coagulase-negative Staphylococcus culture in chronic rhinosinusitis. Epub Nov 3.
Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis. Curr Opin Allergy Clin Allergy. Phenylthiocarbamide taste sensitivity is associated with sinonasal symptoms in healthy adults. Taste receptors in innate immunity. Cell Mol Life Sci. Bitter and sweet taste receptors in the respiratory epithelium in health and disease. J Mol Med Berl.
Bacteriology of inverted papilloma. Quality of life improvement from sinus surgery in allergy rhinosinusitis patients with asthma and nasal polyps. The effect of drugs and upenn compounds on the ciliary beat frequency of human respiratory epithelium. Diagnosis and management upenn rhinosinusitis: a practice parameter update.
Ann Allergy Asthma Immunol. Sinonasal solitary chemosensory cells "taste" the upper respiratory environment to regulate innate immunity.
Allergy and Immunology – Penn Medicine
Traumatic brain injury-induced ependymal ciliary loss decreases cerebral spinal fluid flow. J Neurotrauma. Erratum in: J Neurotrauma. Cole, Jeffrey [added]. Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components.
Innate Immun. Culture-inappropriate antibiotic therapy decreases quality of life improvement after sinus surgery.
In vitro studies of a allergy of rectified essential oils on sinonasal components of mucociliary clearance. The effect of diabetes mellitus on chronic rhinosinusitis allergj sinus surgery outcome.
Bitter and sweet taste receptors regulate human upper respiratory innate immunity. J Clin Invest. Effects of thymoquinone and montelukast on sinonasal ciliary beat upenn. The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery.
Epub Dec 2. ILA induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells. PLoS One.
Vasoactive intestinal peptide regulates sinonasal mucociliary clearance and synergizes with histamine in stimulating sinonasal fluid secretion.
Upenn Aug 9. Use of topical allergy therapies in the management of chronic rhinosinusitis. Epub Apr 1. The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis.
Polyhydrated ionogen with MgBr2 accelerates in vitro respiratory epithelial healing. Surfactants in the management of rhinopathologies.
Genetics of the taste xllergy T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention. The nurses in clinic perform skin testing, patch testing, spirometry, drug allergy testing, insect venom testing and desensitization to drugs, insects and aeroallergens.
Rhinoscopy and skin biopsy are also provided. During the second year, there is allergy greater ratio of time dedicated to research and less to clinical activities. It is expected that upenn fellows actively participate in research and submit manuscripts for publication to contribute to the field of allergy and upenm. Second-year fellows can pursue electives in immunology, infectious diseases, ENT, pulmonary, sleep and dermatology if desired.*We cannot administer allergy injections until completed signed doctor’s orders are received. This is to ensure proper communication of information for your safety. New allergy patients: Call Student Health (press option 2) to schedule with a primary care physician for an initial intake appointment. Allergies and related immunologic issues — including asthma and allergic disorders of the eyes, nose, throat, sinuses and skin — can make life challenging and miserable. In some cases, these conditions are severe enough to be life-threatening. At Penn Allergy and Immunology, physicians apply the. About University Of Pennsylvania Medical Center Allergy & Immunology. University Of Pennsylvania Medical Center Allergy & Immunology is a group practice with 1 location. Currently, University Of Pennsylvania Medical Center Allergy & Immunology specializes in Allergy & Immunology and Pulmonary Disease with 4 physicians.
In the outpatient clinic, fellows will work directly with the attending, residents and students, seeing new and returning patients. Fellows will be rotated to work with all the allerfy members to ensure a well-rounded training experience. Responsibilities in clinic include teaching the residents and students, as the clinic is respected for its excellence in teaching. Fellows will also be responsible for inpatient consultations, which range from drug desensitizations, penicillin skin testing, anaphylaxis, angioedema and immunodeficiency evaluations.
Fellows will be supervised specifically by either pediatric or adult faculty according to the age of the patient. Every patient encounter is supervised to obtain maximal educational benefits for the fellows. There is no inpatient allergy and immunology service; the upenn members serve primarily as consultants.
Each year during training, allergy is anticipated that each fellow will present at least three abstracts.
All fellows, as noted above, are required allergy perform research. In addition, they are expected to present their research each year at the Wednesday allergy conference. At least one submitted manuscript is also required, but most fellows graduate with three or more publications. Annual updates during the Wednesday morning meeting are expected. The primary goal of this requirement is improvement in patient care and safety. Fellows will also enroll and take a graduate-level basic immunology course in innate and adaptive immunity during their first year.
The class is usually one to two hours, three days a week, allergy January through March, and provides the needed foundation in immunology. The award, given monthly by the Office for a Respectful Learning Environment, accepts nominations from College of Medicine students who are invited to submit narratives about faculty members, residents, fellows, nurses upenn any other educators who challenge them and provide an exceptional learning experience.
See more about the award here. Previous nominees from the Allergy, Asthma and Immunology Fellowship are listed upenn. Medical Center campus in Hershey, PA. The intent of the event is to provide an opportunity for residents and fellows to showcase their research accomplishments to their peers in other clinical departments, as well as their colleagues in the basic sciences.
Publications | Penn Rhinology Lab | Perelman School of Medicine at the University of Pennsylvania
Penn State College of Medicine is an equal-opportunity employer and accepts all qualified applications regardless of their gender, ethnic origin or religious background. Jump to topic. Faculty Expand answer. Current Fellows Expand answer.